http://hdl.handle.net/123456789/118 2026-04-09T10:54:11Z 2026-04-09T10:54:11Z Tahir, H. E. Mahunu, G. K Mariod, A. A Xiaobo, Z. Afoakwah, N. A http://hdl.handle.net/123456789/4381 2025-02-11T12:01:30Z 2022-01-01T00:00:00Z

Title: BIOLOGICAL ACTIVITIES OF EVENING PRIMROSE OIL Authors: Tahir, H. E.; Mahunu, G. K; Mariod, A. A; Xiaobo, Z.; Afoakwah, N. A Abstract: In the last decades, many unconventional oils have attracted great attention due to higher biological compounds. Evening primrose oil (Oenothera biennis) is commonly utilized as herbal medicine rich in omega-6 essential fatty acids (i.e., linoleic acid and γ-linoleic acid). The positive effect of EPO has been demonstrated in the case of many diseases such as cyclic breast pain, gestational diabetes, inflammations, cancer, dermatitis, kidney problem, rheumatoid arthritis, oxidative stress, and diabetes mellitus. The present chapter aimed to provide currently available literature related to the biological activities of EPO.

2022-01-01T00:00:00Z Kuuder, C. -J. W. Sulemana, S. S. Yirbekyaa, E. K. http://hdl.handle.net/123456789/3906 2023-02-14T14:04:01Z 2020-01-01T00:00:00Z

Title: RESIDENTS’ PERCEPTIONS OF AND PARTICIPATION IN RURAL TOURISM DEVELOPMENT: ACUMENS FROM KARIMENGA COMMUNITY IN GHANA Authors: Kuuder, C. -J. W.; Sulemana, S. S.; Yirbekyaa, E. K. Abstract: Rural tourism development in contemporary times is viewed with a participatory approach lens thus allowing local residents to benefit. This study assessed tourism development in Karimenga, a community in the West Mamprusi District with a facility dubbed the “Greenhouse Tourism Project”. It also assessed the perception of residents on their participation in tourism and equally explored the impact of tour ism development in the community. Employing both quantitative and qualitative approaches, data were sourced from a sample of 112 residents through questionnaire administration and In-depth Interview (IDI) schedules. The study revealed that the majority of the residents (67%) were involved in tourism decision making. It is recommended that benefits from tourism be made to ‘spiral’ the community to reach most households through loans granted by the assembly for handicraft work to enhance souvenir trade.

2020-01-01T00:00:00Z Appiah, K. A. A. Amoah, G Maison, P. O. M. Yenli, E. M. T. Gyasi-Sarpong, C. K. Azorliade, R. Otu-Boateng, K. Adofo, C. K. Addae, J. B. Frimpong-Twumasi, B. Antwi, I. O. Mintah, D. A Ametih, R. K. http://hdl.handle.net/123456789/3885 2023-02-13T08:49:37Z 2020-01-01T00:00:00Z

Title: GLANULOPLASTY WITH ORAL MUCOSA GRAFT FOLLOWING TOTAL GLANS PENIS AMPUTATION: AN OVERVIEW Authors: Appiah, K. A. A.; Amoah, G; Maison, P. O. M.; Yenli, E. M. T.; Gyasi-Sarpong, C. K.; Azorliade, R.; Otu-Boateng, K.; Adofo, C. K.; Addae, J. B.; Frimpong-Twumasi, B.; Antwi, I. O.; Mintah, D. A; Ametih, R. K. Abstract: Glanuloplasty following amputation of the glans penis can be very daunting for the urologist. The management of penile glans amputation depends on the duration before presentation. In the acute phase, management usually involves auto-transplantation. The use of skin grafts, scrotal flaps and pedicled myocutaneous flaps have been described for penile glans reconstruction following amputation of the glans penis. However, these techniques are fraught with their own peculiar challenges. This chapter is an overview of the management of penile glans amputation and a description of the technique of neo-glans reconstruction using oral mucosa graft.

2020-01-01T00:00:00Z Dongdem, J. T. Wezena, C. A. http://hdl.handle.net/123456789/3629 2022-06-16T11:13:02Z 2021-01-01T00:00:00Z

Title: FUNCTIONAL SIGNIFICANCE OF THE E3 UBIQUITIN LIGASES IN DISEASE AND THERAPEUTICS Authors: Dongdem, J. T.; Wezena, C. A. Abstract: E3 ubiquitin ligases of which there are >600 putative in humans, constitute a family of highly heterogeneous proteins and protein complexes that are the ultimate enzymes responsible for the recruitment of an ubiquitin loaded E2 ubiquitin-conjugating enzyme, recognise the appropriate protein substrate and directly or indirectly transfer the ubiquitin load onto the substrate. The aftermath of an E3 ligase activity is usually the formation of an isopeptide bond between the free carboxylate group of ubiquitin’s C-terminal Gly76 and an ε-amino group of the substrate’s Lys, even though non-canonical ubiquitylation on non-amine groups of target proteins have been observed. E3 ligases are grouped into four distinct families: HECT, RING-finger/U-box, RBR and PHD-finger. E3 ubiquitin ligases play critical roles in subcellular signalling cascades in eukaryotes. Dysfunctional E3 ubiquitin ligases therefore tend to inflict dramatic effects on human health and may result in the development of various diseases including Parkinson’s, Amyotrophic Lateral Sclerosis, Alzheimer’s, cancer, etc. Being regulators of numerous cellular processes, some E3 ubiquitin ligases have become potential targets for therapy. This chapter will present a comprehensive review of up-to-date findings in E3 ligases, their role in the pathology of disease and therapeutic potential for future drug development.

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